Researcher PhD Student

We are seeking a predoctoral scientist passionate about conducting patient-centered research, who is committed to focusing their scientific career on projects aimed at improving the treatment options for pediatric cancer patients, particularlly rhabdomyosarcoma (RMS).

The candidate will join an ongoing research project funded by private sources, focused on developing new drugs for pediatric RMS patients. The selected candidate will work in our hospital research center, collaborating with multidisciplinary teams, including clinicians, bioinformatics experts, statisticians, and pharmaceutical companies.

Main tasks and responsibilities:

• The collection, and processing of biological samples from rhabdomyosarcoma tumors and cell lines. Conduct research using molecular biology techniques, including primary cell cultures.
• Participate in the design and execution of in vivo studies using patient derived xenografts models to evaluate the effectiveness of new treatments.
• Perform functional in vitro studies in cultured cells using molecular techniques such as CRISPR/CAS9 technology, flow cytometry, transcriptomic and proteomic analysis etc.
• Collaborate with multidisciplinary teams, including clinicians, bioinformaticians, statisticians, and pharmaceutical companies, to advance the project's goals.

Requirements:

Candidate Requirements:
• Bachelor's degree in Pharmacy, Biology, Biomedicine, Medicine, or related fields.
• Willingness to work with patient-derived xenograft mouse models.
• Some Practical experience with core wet-lab techniques such as RT-PCR, immunoblotting, immunofluorescence, and cell culture is preferred.
• Integrity, resilience, teamwork, organizational and communication skills.
• Motivation for a career in translational cancer research.

Desirable Qualities:
• Experience in translational research with murine models (drug administration, mouse surgery, mouse models pharmacokinetics...) is highly valued.
• Demonstrated interest in pharmacology, target therapy, immunotherapy or molecular biology.
• Maintain a proactive attitude, active listening skills and the ability to work effectively in a collaborative environment.

What We Offer:
• An opportunity to work on a meaningful project with real-world impact in pediatric cancer treatment.
• Inter- and multi-disciplinary collaboration between groups.
• Customized training and ample career development opportunities.
• Participate in specialized courses and workshops and congresses
• Be part of an expert, young, dynamic, innovative and enthusiastic team focused on the improvement of the diagnosis, treatment and quality of life of paediatric cancer patients.
• Enjoy a professional work environment.
• All people receive consideration for our vacant position, without distinction of gender, age, race, religion, identity, sexual orientation, origin, disability or any other characteristic.